Our group studies the molecules and mechanisms that govern the polarity, growth, and morphogenesis of epithelia, the fundamental tissue of all animals and the major constituent of human organs. We also use Drosophila cancer models as a simple system to understand both how epithelial organization prevents tumor formation and how tumors actually kill their hosts.

 

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      Now out in Annu Rev Cancer Biol: "Beyond Mice and Men." We think of cancer as a disease of humans, as well as pets 🐈‍⬛ 🐕 & lab mice. But cancer is found across the animal tree of life, including clams and fruit flies. Comparative oncology has a lot to teach us. 🧵 https://www.annualreviews.org/content/journals/10.1146/annurev-cancerbio-070524-040234
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      And so fabulous to dine out with former postdocs Anne Classen @classenlab.bsky.social, Thomas Vaccari @vaccarilab.bsky.social and Lucy O’Brien. Many laughs, fond memories, and talk of bright futures for all of them. #EDRC2025
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      Honored to share stage with all the great plenary speakers at #EDRC2025. Exciting science and great vibes from Drosophila researchers worldwide – Let’s keep the American, Euro, and APAC communities coordinated and strong!